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Mouse Models of Human Cancer database
JAX PDX
Data Resource:  JAX PDX
Point of Contact:  
Debra M. Krupke, MS; Dale A. Begley, PhD,  
Xenograft

About This Dataset
The Mouse Models of Human Cancer database (MMHCdb) is an expertly curated compendium of in vivo mouse models of human cancer. To ensure maximum data accessibility and compatibility we follow strict adherence to community nomenclature standards, ontologies, and minimal information standards. This work benefits cancer researchers by making it easier to aggregate information from the same or related mouse models. It is fundamental to making mouse models of human cancer and their associated data Findable, Accessible, Interoperable, and Reusable (FAIR). We also facilitate the informed selection and use of mouse models by highlighting the impact that genetic background has on key cancer characteristics, including cancer susceptibility, the spectrum of tumor types and frequencies observed in a model, age of tumor onset/detection, and metastatic potential.
Core Data Elements
Number of Cases
56
Case Sex
Female (25); Male (30); Other (1)
Case Age At Diagnosis
0 to 4 years (6); 5 to 9 years (9); 10 to 14 years (10); 15 to 19 years (1); 20 to 24 years (11); 25 to 29 years (1); 30 to 34 years (6); 35 to 39 years (12)
Case Race
Not Reported (56)
Case Ethnicity
Not Reported (56)
Case Disease Diagnosis
Acute Lymphocytic Leukemia (1); Adenocarcinoma (1); Alveolar Rhabdomyosarcoma (10); B-Cell Adult Acute Lymphocytic Leukemia (3); Brain Glioma (2); Colon Adenocarcinoma (2); Colon Carcinoma (1); Embryonal Rhabdomyosarcoma (1); Epithelioid Sarcoma (1); Ewing Sarcoma (1); Glioblastoma (1); Invasive Ductal Carcinoma (9); Kidney Rhabdoid Cancer (1); Neuroblastoma (2); Osteosarcoma (4); Pediatric Ependymoma (1); Pediatric Osteosarcoma (2); Renal Cell Carcinoma (1); Rhabdoid Cancer (1); Rhabdomyosarcoma (3); Sarcoma (5); Synovial Sarcoma (2); T-Cell Adult Acute Lymphocytic Leukemia (1)
Case Tumor Site
Adrenal gland (1); Bone (6); Bone marrow (5); Brain (8); Breast (9); Chest wall (1); Colon (1); Head (1); Liver (5); Lung (7); Lymph node (2); Muscle (1); Oral cavity (1); Other (2); Pancreas (1); Soft tissue (3); Spine (2)
Additional Data Elements
DATA REPOSITORY
Grant Information
R01CA089713
Electronic Access to Mouse Tumor Data
Published In
https://doi.org/10.1093/nar/gky984
Charts
Male (30); Female (25); Other (1)
30Male